Appropriateness of repetitive therapeutic drug monitoring and laboratory turnaround time

Therapeutic Drug Monitoring of Sirolimus,Correlation With Laboratory Parameters In Transplant Patients

Sirolimus is a potent immunosuppressive agent administered as prophylactic agent to prevent rejection after organ transplantation. Sirolimus must be used within a narrow therapeutic window. Due to inter- and intra-variability, sirolimus blood concentrations may be affected, therefore, there is no possibility of predicting the sirolimus blood concentrations based on the dose patients received. T...

Monitoring of Turnaround time (TAT) in Biochemistry Laboratory of a tertiary care hospital in Punjab

Turnaround time (TAT) is commonly defined as the time from when a test is ordered until the result is reported which includes the preanalytical, analytical and post-analytical time. Increased attention to patient’s needs is demonstrated by efforts to improve the quality of the entire service provided, e. g reduction of laboratory turnaround time (TAT). The availability of the results from a lab...

A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs

Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...

therapeutic drug monitoring

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Posaconazole therapeutic drug monitoring: a reference laboratory experience.